Tirzepatide Reconstitution: Calculator & Step-by-Step Instructions

Complete tirzepatide reconstitution guide with calculator examples, step-by-step mixing instructions, titration schedule, and storage guidelines.

Understanding Tirzepatide Dosing

Tirzepatide requires careful reconstitution when using compounded versions. This guide walks through the complete process from mixing to administration.

Tirzepatide Vial Sizes

Compounded tirzepatide commonly comes in these vial sizes:

  • 5mg vials (starter dosing)
  • 10mg vials (mid-range dosing)
  • 15mg vials (higher dosing)
  • 30mg vials (multiple doses)

Reconstitution Calculator

Use our Peptide Calculator for precise measurements. Here are common examples:

5mg Vial Reconstitution

BAC WaterConcentration2.5mg Dose5mg Dose
1mL5mg/mL50 units100 units
2mL2.5mg/mL100 unitsNot possible

10mg Vial Reconstitution

BAC WaterConcentration2.5mg Dose5mg Dose7.5mg Dose
2mL5mg/mL50 units100 unitsN/A
4mL2.5mg/mL100 unitsN/AN/A

30mg Vial Reconstitution

BAC WaterConcentration5mg Dose7.5mg Dose10mg Dose
3mL10mg/mL50 units75 units100 units
6mL5mg/mL100 unitsN/AN/A

Step-by-Step Reconstitution

Step 1: Gather Supplies

  • Tirzepatide vial
  • Bacteriostatic water
  • Insulin syringes (29-31 gauge)
  • Alcohol swabs

Step 2: Calculate Water Amount

Decide on your desired concentration. Lower concentrations are easier to measure small doses.

Step 3: Clean and Inject Water

Wipe both vial tops with alcohol. Draw the calculated water amount and inject slowly down the vial wall. Never spray directly on the powder.

Step 4: Mix Gently

Let sit for 5-10 minutes, then gently roll between palms. Never shake the vial.

Tirzepatide Titration Schedule

WeeksWeekly Dose
1-42.5mg
5-85mg
9-127.5mg
13-1610mg
17-2012.5mg
21+15mg (maintenance)

Storage After Reconstitution

  • Refrigerate immediately after mixing
  • Use within 28-30 days
  • Keep away from light
  • Never freeze reconstituted tirzepatide

Need Help Calculating?

Our Peptide Reconstitution Calculator makes it easy to determine exactly how much water to add and how many units to draw for any dose.