FOXO4-DRI

A designed peptide studied for clearing ageing "senescent" cells in mice.

What it is

FOXO4-DRI is a modified peptide that interferes with the FOXO4 and p53 interaction.

How it works

In mouse studies, blocking that interaction pushed senescent cells to die off.

What it is researched for

• Senescent cells in animal models

Research status

Preclinical. No completed human trials.

What to watch for

• Unknown effects in humans

Storage

Lyophilised powder keeps in the freezer or fridge, away from light. Once mixed with bacteriostatic water, keep it refrigerated and use it within about four weeks.

Common questions

Is FOXO4-DRI approved for human use?

Preclinical. No completed human trials.

Where can I read the research on FOXO4-DRI?

Use the PubMed, Europe PMC and clinical trials buttons on this page. They run a live search for FOXO4-DRI, so you see what is published today.

Educational reference only, not medical advice.