GHK-Cu

A copper binding peptide with the best evidence of any skin peptide.

What it is

GHK-Cu is a three amino acid sequence bound to copper. It occurs naturally in human plasma and drops sharply with age.

How it works

It raises collagen and elastin production, supports wound repair, and influences a long list of genes tied to tissue remodelling. Topical use is the best documented route.

What it is researched for

• Skin firmness and fine lines
• Wound healing
• Hair follicle size
• Scar appearance

Research status

Well documented in dermatology literature for topical use. Injectable use is research only.

What to watch for

• Skin irritation when combined with strong vitamin C or acids
• Copper accumulation with heavy long-term systemic use
• Blue tint on the skin from the copper colour, which washes off

Storage

Keep topical serums out of sunlight. Lyophilised powder follows standard fridge or freezer storage.

Common questions

Topical or injected?

For skin and hair, topical carries the stronger evidence and the lower risk.

Can it be used with retinol?

Most guidance suggests alternating nights rather than layering them together.

Educational reference only, not medical advice.