Melanotan I
A melanocortin peptide approved as an implant for a rare light sensitivity condition.
What it is
Afamelanotide is a synthetic version of alpha-MSH, the hormone that drives tanning.
How it works
It acts on MC1R receptors in skin and increases melanin.
What it is researched for
- Erythropoietic protoporphyria
- Skin pigmentation
Research status
Approved as an implant for one rare condition. Injectable versions sold online are unapproved.
What to watch for
- Nausea
- New or darker moles
- Flushing
Storage
Lyophilised powder keeps in the freezer or fridge, away from light. Once mixed with bacteriostatic water, keep it refrigerated and use it within about four weeks.
Common questions
Is Melanotan I approved for human use?
Approved as an implant for one rare condition. Injectable versions sold online are unapproved.
Where can I read the research on Melanotan I?
Use the PubMed, Europe PMC and clinical trials buttons on this page. They run a live search for Melanotan I, so you see what is published today.
Educational reference only, not medical advice.