MK-677

An oral ghrelin-receptor agonist, technically not a peptide.

What it is

MK-677 is a small molecule that mimics ghrelin. It is often grouped with peptides because it works on the same system.

How it works

It activates the ghrelin receptor and raises growth hormone and IGF-1 over the day.

What it is researched for

• Growth hormone and IGF-1
• Sleep
• Muscle loss in older adults

Research status

Investigational. Not approved for human use.

What to watch for

• Hunger
• Water retention
• Blood sugar changes

Storage

Store as directed by the supplier, sealed and dry.

Common questions

Is MK-677 approved for human use?

Investigational. Not approved for human use.

Where can I read the research on MK-677?

Use the PubMed, Europe PMC and clinical trials buttons on this page. They run a live search for MK-677, so you see what is published today.

Educational reference only, not medical advice.